Discussion on mouse intestinal eosinophils before and after allergen challenge, and in a chronic inflammation model focusing on subtypes that differ in CD11c surface expression.

A dynamic continuum of CD11c expression provides a framework for tracking sub-phenotype versatility of intestinal eosinophils in health and disease.

SNHG8 reduced microglia activation and blood-brain barrier permeability via the miR-449c-5p/SIRT1/SIRT1/FoxO1 pathway, thus playing a protective role in ischemic brain injury.

mTORC2-dependent Akt activation is instrumental for metabolic reprogramming at the early stages-migration and differentiation-of macrophage-mediated immunity.

CTCF is a translocation partner of ETO2 in acute myeloid leukemia; aids in understanding the pathogenic mechanisms in AML and may have future prognostic value.

M1 polarization primes macrophages to transition into a distinct M2 phenotype when compared with M2 macrophages derived from M0.

The transcription factor c-Rel regulates intestinal homeostasis and protects against pathogen colonization; c-Rel-deficient mice display defective IgA production in the intestine.

BCG immune training before pregnancy led to IUGR in mice by modifying immune cell frequency in the developing placenta, whereas LPS training had no effect

Flunarizine limits Mycobacterium tuberculosis growth in macrophages by promoting CaM-pCAMKII-mediated phagolysosome maturation.

Whereas the numbers of the main NK cells subsets are normal in M. tuberculosis-infected patients, detailed phenotypic characterization revealed several differences related to functional modifications.

Stem cells from human exfoliated deciduous teeth (SHED)-mediated rescue of Treg/Th17 balance via the sPD-L1/PD-1 pathway ameliorates the gland inflammation and dryness symptoms in SS mice, suggesting that SHED are a promising source for treating autoimmune diseases in a clinical setting.

CDK regulation of neutrophil function as a potential target in neutrophil-dominant inflammatory diseases.

Periodontitis and its treatment are associated with minor but consistent alterations in circulating inflammatory cell profiles. These changes could be a mechanism linking periodontitis to systemic diseases.

This review examines the role of antibodies in sub-clinical malaria, focusing on antibody development, and functional mechanisms, and epidemiological studies to inform malaria control interventions.

In severe COVID-19 patients, VIP plasma levels correlated with decreased inflammatory markers and survival. In in vitro assays with monocytes and lung epithelial cells, VIP and PACAP were found to decrease SARS-CoV-2 RNA synthesis (monocytes) and viral replication (lung epithelial cells). Both neuropeptides also reduced inflammatory factors and cell death of infected cells.