 |
Journal of Leukocyte Biology
Early View
Online Version of Record before inclusion in an issue
|
NeuroImmunoEndocrinology: A brief historic narrative
María Dolores Ponce-Regalado, Gilberto Pérez-Sánchez, Oscar Rojas-Espinosa, Patricia Arce-Paredes, M Iván Girón-Peréz, Lenin Pavón-Romero, Enrique Becerril-Villanueva
Version of Record online:31 January 2022
Graphical Abstract
Neuroimmunoendocrinology is has established its place as a biomedical discipline worldwide in the past 70 years.
Open Access
Cytosolic dsRNA improves neonatal innate immune responses to adjuvants in use in pediatric vaccines
Kiva Brennan, Simon Craven, Maria Cheung, Daniel Kane, Eleanor Noone, Joseph O'Callaghan, Eleanor J Molloy, Patrick T Walsh, Fionnuala M McAuliffe, Sarah L Doyle
Version of Record online:31 January 2022
Graphical Abstract
Cytosolic dsRNA activity in neonatal myeloid cells as a pediatric adjuvant.
Multifactorial assessment of neutrophil chemotaxis efficiency from a drop of blood
Felix Ellett, Anika L. Marand, Daniel Irimia
Version of Record online:31 January 2022
Graphical Abstract
Dynamic sensitivity range of neutrophils to mechanical and chemical cues is determined.
CAR NK‐92 cells targeting DLL3 kill effectively small cell lung cancer cells in vitro and in vivo
Manting Liu, Wensou Huang, Yongjian Guo, Yubo Zhou, Cheng Zhi, Jingwu Chen, Junping Li, Jinping He, Hui Lian, Jingwen Zhou, Xiaodie Ye, Yuling Hu, Hong Hu, Zhaoyuan Liu, Jingjun Huang, Liteng Lin, Mingyue Cai, Xiaobin Wang, Jingzhen Huang, Zhenfeng Zhang, Kangshun Zhu, Qi Zhao, Bihui Cao
Version of Record online:28 January 2022
Graphical Abstract
DLL3-CAR NK-92 cells showed significant anti-tumor effect on small cell lung cancer both in vitro and in vivo.
Free Access
Opposing roles for sMAdCAM and IL‐15 in COVID‐19 associated cellular immune pathology
Amit Kumar Singh, Nandini Kasarpalkar, Shilpa Bhowmick, Gaurav Paradkar, Mayur Talreja, Karan Shah, Abhishek Tiwari, Harsha Palav, Snehal Kaginkar, Rajiv Kulkarni, Ashwini Patil, Varsha Kalsurkar, Sachee Agrawal, Jayanthi Shastri, Rajesh Dere, Ramesh Bharmal, Smita D. Mahale, Vikrant M. Bhor, Vainav Patel
Version of Record online:24 January 2022
Graphical Abstract
A mucosal and lymphocyte migration marker (sMAdCAM) and IL-15, a cytokine regulating leukocyte activation and homeostasis, are associated with different states of immune pathology following COVID-19.
Open Access
Concurrent stimulation of monocytes with CSF1 and polarizing cytokines reveals phenotypic and functional differences with classical polarized macrophages
Liying An, Julia Michaeli, Prama Pallavi, Annette Breedijk, Xin Xu, Nadine Dietrich, Martin Sigl, Michael Keese, Katja Nitschke, Jonas Jarczyk, Philipp Nuhn, Bernhard K. Krämer, Benito A. Yard, Jan Leipe
Version of Record online:24 January 2022
Graphical Abstract
Concurrent stimulation of monocytes with CSF1 and IL-4 generates polarized M2 macrophages that support T-cell proliferation in a COX-1 dependent manner upon LPS stimulation.
Pan‐cancer analysis of GALNTs expression identifies a prognostic of GALNTs feature in low grade glioma
Chengzhou Mao, Shi-Min Zhuang, Zijin Xia, Zhi-Wen Xiao, Chun-Xia Huang, Qiang Su, Jun Chen, Jing Liao
Version of Record online:24 January 2022
Graphical Abstract
Development of a novel prognostic biomarker for LGG that may support evauation of immunotherapy strategies in brain cancer.
IL‐27 signaling negatively regulates FcɛRI‐mediated mast cell activation and allergic response
Xiaopeng Wan, Yuanyuan Zhang, Huanna Tang, Mengyao Li, Tianqi Jiang, Jia He, Chunjing Bao, Junkai Wang, Yinjing Song, Peng Xiao, Yang Liu, Lihua Lai, Qingqing Wang
Version of Record online:24 January 2022
Graphical Abstract
IL-27 signaling negatively regulates mast cell mediated allergic response by increasing activation of Grb2-PLC-γ1-SLP-76, PI3K/Akt/IkBa signaling and decreasing SHP-1 phosphorylation.
TREM‐1 is required for enhanced OpZ‐induced superoxide generation following priming
Shubha Murthy, Sankar Baruah, Jayden L. Bowen, Kathy Keck, Brett A. Wagner, Garry R. Buettner, David B. Sykes, Julia Klesney-Tait
Version of Record online:24 January 2022
Graphical Abstract
TREM-1 is required for primed neutrophil oxidative burst
Open Access
PD‐L1 expression in peripheral blood granulocytes at diagnosis as prognostic factor in classical Hodgkin lymphoma
Annarosa Cuccaro, Silvia Bellesi, Eugenio Galli, Ilaria Zangrilli, Francesco Corrente, Elisa Cupelli, Federica Fatone, Elena Maiolo, Eleonora Alma, Marcello Viscovo, Francesco D'Alò, Salvatore Annunziata, Maurizio Martini, Vittoria Rufini, Alessandro Giordano, Valerio De Stefano, Luigi Maria Larocca, Stefan Hohaus
Version of Record online:20 January 2022
Graphical Abstract
Expression of PD-L1 in peripheral blood reflects disease burden and predicts interim PET result and prognosis in classical Hodgkin lymphoma.
The role of naturally acquired antimalarial antibodies in subclinical Plasmodium spp. infection
Katherine O'Flaherty, Merryn Roe, Freya J.I. Fowkes
Version of Record online:20 January 2022
Graphical Abstract
This review examines the role of antibodies in sub-clinical malaria, focusing on antibody development, and functional mechanisms, and epidemiological studies to inform malaria control interventions.
Molecular and immune interactions between β‐ and γ‐herpesviruses in the immunocompromised host
Yessica Sánchez-Ponce, Ezequiel M. Fuentes-Pananá
Version of Record online:20 January 2022
Graphical Abstract
Clinical and molecular evidence of putative interactions between β- and γ-herpesviruses that cause or worsen pathological disorders
Free Access
Neutrophil subsets and their differential roles in viral respiratory diseases
Yuning Zhang, Quanbo Wang, Charles R Mackay, Lai Guan Ng, Immanuel Kwok
Version of Record online:18 January 2022
Graphical Abstract
Review on the role neutrophils play during viral respiratory diseases, evaluating their various pro- and anti- viral functions leading to disease resolution or pathology.
Open Access
Immune modulatory effects of progesterone on oxLDL‐induced trained immunity in monocytes
Laszlo A. Groh, Dagmar E. Verel, Charlotte D.C.C van der Heijden, Vasiliki Matzaraki, Simone J.C.F.M. Moorlag, L. Charlotte de Bree, Valerie A.C.M. Koeken, Vera P. Mourits, Samuel T. Keating, Jelmer H. van Puffelen, Leo A. B. Joosten, Mihai G. Netea, Niels P. Riksen
Version of Record online:17 January 2022
Graphical Abstract
Cytokine production by oxLDL-induced trained immunity is inhibited by the steroid hormone progesterone.
Hemagglutinin‐based DNA vaccines containing trimeric self‐assembling nanoparticles confer protection against influenza
Yongbo Qiao, Shenghui Jin, Jiaojiao Nie, Yaotian Chang, Bo Wang, Shanshan Guan, Qinghan Li, Yuhua Shi, Wei Kong, Yaming Shan
Version of Record online:17 January 2022
Graphical Abstract
Self-assembled ferritin nanoparticles displaying influenza virus hemagglutinin trimer induce robust immune responses and protection against H1N1 virus
Maternal–fetal tolerance: Not just a uterine affair
Timothy J. Boly, Jennifer R. Bermick
Version of Record online:10 January 2022
Graphical Abstract
Discussion on systemic maternal immune cells aiding in maternal-fetal tolerance during pregnancy.
SUZ12 participates in the proliferation of PNH clones by regulating histone H3K27me3 levels
Yingying Chen, Hui Liu, Lijie Zeng, Liyan Li, Dan Lu, Zhaoyun Liu, Rong Fu
Version of Record online:06 January 2022
Graphical Abstract
SUZ12 overexpression in abnormal clones in PNH patients regulates cell proliferation, apoptosis and the cell cycle by affecting the trimethylation level of H3K27 , thus conferring proliferation advantages to abnormal PNH clones, which then participate in the pathogenesis of PNH.
Periodontal ligament stem cells promote polarization of M2 macrophages
Jiani Liu, Hong Wang, Ludan Zhang, Xiaoyu Li, Xiaoling Ding, Gang Ding, Fulan Wei
Version of Record online:04 January 2022
Graphical Abstract
PDLSCs could promote M2 macrophage polarization and enhanced IL-4 and IL-13-induced M2 macrophage polarization via JNK pathways.
Open Access
Crosstalk between R848 and abortive HIV‐1 RNA‐induced signaling enhances antiviral immunity
Melissa Stunnenberg, John L. van Hamme, Esther M. Zijlstra-Willems, Sonja I. Gringhuis, Teunis B.H. Geijtenbeek
Version of Record online:04 January 2022
Graphical Abstract
Abortive HIV-1 RNA modulates TLR7/8-dependent signaling to induce effective antiviral innate and adaptive immunity in human dendritic cells.
|