Gretchen Diehl

In graduate school at Berkeley I worked with Astar Winoto and generated a knockout mouse that responded to infection with stronger NfkB signaling. For my postdoc with Dan Littman at NYU, I focused on intestinal immunity to understand regulation of a natural route of infection. There, I found the microbiota restrained trafficking of mononuclear phagocytes from intestine to mesenteric lymph node, limiting induction of mucosal immune responses. I continued with this theme in my own lab at Baylor. Our recent publication demonstrates intestinal microbes are key for innate immune cell anti-inflammatory signals.