Discussion on TRPM8 function in monocyte differentiation and disease emphasizes the need for future characterization of cation channel mechanisms.

TRPM8 in human monocytes promotes aspects of their differentiation to macrophages and acts at a critical early time point to limit inflammatory potential.

The study demonstrate that the PI3K-δ inhibitor Seletalisib impairs maturation of DCs while increasing expression of chemokine receptor involved in DC migration toward lymph nodes

Inflammation causes an increase in neutrophil half-life at the inflammatory site and reduces bone marrow maturation time

IL-27 signaling negatively regulates mast cell mediated allergic response by increasing activation of Grb2-PLC-γ1-SLP-76, PI3K/Akt/IkBa signaling and decreasing SHP-1 phosphorylation.

IL-17A aggravates asthma-induced intestinal immune injury by promoting neutrophil trafficking, which facilitates the explorations for new potential biomarkers for the treatment of asthma.

Concurrent stimulation of monocytes with CSF1 and IL-4 generates polarized M2 macrophages that support T-cell proliferation in a COX-1 dependent manner upon LPS stimulation.

The nuclear protein DEK acts as a chemotactic factor for hematopoietic stem and progenitor cells in a CXCR2- and Gαi protein-coupled signaling-dependent manner.

TREM-1 is required for primed neutrophil oxidative burst

By inducing Klf10 expression, Mycobacterium tuberculosis decreases INF-γ production and impairs an INF-γ-mediated autocrine loop that promotes macrophages macropinocytosis, thus favoring survival and infection.

Ascorbic acid inhibits both the production of pro-inflammatory cytokines and the upregulation of CD16 and CD163 in LPS or LTA polarized monocytes in vitro.

AM-derived responsive protein, NRP2, protects the lungs from unwanted injury by promoting the clearance of invading pathogens.

Genomic landscape enhanced the understanding of the biological differences of ALL.

Cytosolic dsRNA activity in neonatal myeloid cells as a pediatric adjuvant.

Expression of PD-L1 in peripheral blood reflects disease burden and predicts interim PET result and prognosis in classical Hodgkin lymphoma.

Self-assembled ferritin nanoparticles displaying influenza virus hemagglutinin trimer induce robust immune responses and protection against H1N1 virus

Review of potential correlates of beneficial patient response to IL-12 therapy in the treatment of cancer.

Monocytes and monocyte-derived macrophages express minimal ACE2 and TMPRSS2 and resist SARS-CoV-2 Spike-mediated infection, suggesting direct myeloid cell infection is unlikely a major contributor to pathogenesis.