Post Doctoral Scientist - Research Microbial Pathogenesis- Dr. Bagaitkar's lab

 

Bagaitkar Lab located in the Center for Microbial Pathogenesis at Nationwide Children’s Hospital invites applications for postdoctoral fellows in immunology and microbiology. The successful applicant will join a research project looking at inherited defects in NADPH oxidase modulate host inflammatory responses at the oral mucosal barrier. The NIH-funded research project focuses on understanding the role of oxidants in modulating neutrophil and macrophage effector responses in a manner that promotes immune homeostasis at the oral and other mucosal barriers. This is a full-time, 12-month appointment with the possibility of yearly renewal dependent upon performance and continued funding of 3 to a maximum of 5 years.

 

Schedule: (Full time, Benefits Eligible)

 

Location:

Wexner Center

700 Children's Dr

Columbus, Ohio 43205

Why Nationwide Children's Hospital?

The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children’s Hospital, where Passion Meets Purpose.

Here, Everyone Matters. We’re 12,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we’ll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere.

Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere.

Nationwide Children’s Hospital. A Place to Be Proud.

Responsibilities

  • Induction of inflammatory injury (experimental periodontitis, aspiration pneumonia, DSS drive colitis and skin irritation) in conditional genetic mouse models.
  • Handling and breeding of mice, isolation of primary blood cells (neutrophils, macrophages, and dendritic cells)
  • Cellular and molecular assays evaluating neutrophil effector functions (Phagocytosis, ROS assays, NETosis, chemotaxis).
  • Isolation and analysis of RNA from cells and tissues (real-time PCR, RNA-seq, RNA-seq, ATAC-seq) 
  • Confocal microscopy, flow cytometry and flow sorting.

Qualifications

KNOWLEDGE, SKILLS AND ABILITIES REQUIRED:

 

Education:

  • PhD in Immunology, Microbiology or a related discipline.

EOE M/F/Disability/Vet

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